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Season 2 • Episode 3

AI and the future of neurosurgery | Radiology Rewired

Episode overview

AI is increasingly impacting neurosurgery and the future of the OR. In this episode of Radiology Rewired, we welcome Dr. Sabareesh Natarajan, a triple-trained neurosurgeon, neurointerventionalist, and radiation specialist in San Diego.

As both a practicing surgeon and the founder of his own neuroscience practice, Dr. Natarajan brings a rare vantage point: clinician, entrepreneur, and systems thinker. He argues that AI's real promise isn't pattern recognition—it's precision medicine. It's an approach to breaking down the silos that slow acute care, and delivering expert-level treatment no matter where a patient lives.

We get into the ideas reshaping neuroscience: how AI-connected platforms are compressing the time from stroke detection to intervention, why "finding your patient's twin" across thousands of hospitals could guide the best treatment, how robotics and teleoperation could bring remote surgery to underserved communities, and why breaking down clinical silos may matter as much as any single algorithm.

About the host

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Vivek Singh, MD
Neuroradiologist, MUSC

Dr. Singh is a board-certified neuroradiologist and assistant professor at MUSC, where he completed his diagnostic radiology residency and neuroradiology fellowship, serving as chief resident in his final year. His expertise spans the full spectrum of diagnostic imaging, with a strong interest in stroke and brain tumor imaging, while also regularly interpreting general studies and performing a range of image-guided procedures.

A graduate of the Virginia Tech Carilion School of Medicine with dual undergraduate degrees in Human Nutrition and Biochemistry from Virginia Tech, Dr. Singh developed a deep interest in AI during training. He focuses on how AI can improve early disease detection, expand therapeutic imaging, enhance screening programs, and triage critical findings. He is particularly interested in the evolving role of radiologists as information integrators, combining AI insights with imaging, genomics, and clinical data to guide diagnosis and treatment.

About the guest

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Sabareesh Natarajan, MD, MS
Open Vascular, Endovascular & Skull Base Neurosurgeon, Sharp Health

Dr. Sabareesh Natarajan is a double board-certified neurosurgeon and neurointerventional surgeon at Sharp HealthCare and Founder & CEO of the Brain, Spine & Vascular Neuroscience Institute. He specializes in stroke, cerebrovascular disease, brain tumors, and complex spine conditions, with expertise spanning both open surgical and minimally invasive endovascular techniques. He previously held academic and leadership roles at the University of Massachusetts Medical School, where he led programs in skull base and vascular neurosurgery. Dr. Natarajan has authored over 100 peer-reviewed publications and 30+ textbook chapters, and is widely recognized for his work advancing stroke care, neurovascular treatment, and multidisciplinary care delivery.